Ontology highlight
ABSTRACT:
SUBMITTER: Maity S
PROVIDER: S-EPMC7496235 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Maity Sajal S Hande Madhuri M Lönnberg Tuomas T
Chembiochem : a European journal of chemical biology 20200505 16
Oligonucleotides incorporating a central C-nucleoside with either a rigid or flexible benzaldoxime base moiety have been synthesized, and the hybridization properties of their metallacyclic derivatives have been studied by UV melting experiments. In all cases, the metallated duplexes were less stable than their unmetallated counterparts, and the metallacyclic nucleobases did not show a clear preference for any of the canonical nucleobases as a base-pairing partner. With palladated oligonucleotid ...[more]