Ontology highlight
ABSTRACT:
SUBMITTER: Leiter LA
PROVIDER: S-EPMC7496251 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Leiter Lawrence A LA Bain Stephen C SC Bhatt Deepak L DL Buse John B JB Mazer C David CD Pratley Richard E RE Rasmussen Søren S Ripa Maria Sejersten MS Vrazic Hrvoje H Verma Subodh S
Diabetes, obesity & metabolism 20200603 9
It is unknown if the cardioprotective and renal effects of glucagon-like peptide-1 receptor agonists are consistent across blood pressure (BP) categories in patients with type 2 diabetes and at high risk of cardiovascular events. Using data from the LEADER (9340 patients) and SUSTAIN 6 (3297 patients) trials, we evaluated post hoc the cardiorenal effect of liraglutide and semaglutide on major adverse cardiovascular events (MACE) and nephropathy by baseline BP categories using a Cox proportional ...[more]