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Association of adoption of transradial access for percutaneous coronary intervention in ST elevation myocardial infarction with door-to-balloon time.


ABSTRACT: OBJECTIVES:We aimed to study adoption of transradial primary percutaneous coronary intervention (TR-PPCI) for ST elevation myocardial infarction (STEMI) ("radial first" approach) and its association with door-to-balloon time (D2BT). BACKGROUND:TR-PPCI for STEMI is underutilized in the United States due to concerns about prolonging D2BT. Whether operators and hospitals adopting a radial first approach in STEMI incur prolonged D2BT is unknown. METHODS:In 1,272 consecutive cases of STEMI with PPCI at our hospital from January 1, 2011, to December 31, 2016, we studied TR-PPCI adoption and its association with D2BT including a propensity matched analysis of similar risk TR-PPCI and trans-femoral primary PCI (TF-PPCI) patients. RESULTS:With major increases in hospital-level TR-PPCI (hospital TR-PPCI rate: 2.6% in 2011 to 79.4% in 2016, p-trend<.001) and operator-level TR-PPCI (mean operator TR-PPCI rate: 2.9% in 2011 to 81.1% in 2016, p-trend = .005), median hospital level D2BT decreased from 102?min [81, 142] in 2011 to 84?min [60, 105] in 2016 (p-trend<.001). TF crossover (10.3%; n = 57) was not associated with unadjusted D2BT (TR-PPCI success 91?min [72, 112] vs. TF crossover 99?min [70, 115], p = .432) or D2BT adjusted for study year and presenting location (7.2% longer D2BT with TF crossover, 95% CI: -4.0% to +18.5%, p = .208). Among 273 propensity-matched pairs, unadjusted D2BT (TR-PPCI 98 [78, 117] min vs. TF-PPCI 101 [76, 132] min, p = .304), and D2BT adjusted for study year and presenting location (5.0% shorter D2BT with TR-PPCI, 95% CI: -12.4% to +2.4%, p = .188) were similar. CONCLUSIONS:TR-PPCI can be successfully implemented without compromising D2BT performance.

SUBMITTER: Huded CP 

PROVIDER: S-EPMC7496393 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Association of adoption of transradial access for percutaneous coronary intervention in ST elevation myocardial infarction with door-to-balloon time.

Huded Chetan P CP   Kapadia Samir R SR   Ballout Jad A JA   Krishnaswamy Amar A   Ellis Stephen G SG   Raymond Russell R   Cho Leslie L   Simpfendorfer Conrad C   Bajzer Chris C   Martin Joseph J   Nair Ravi R   Lincoff A Michael AM   Kravitz Kathleen K   Menon Venu V   Hantz Scott S   Khot Umesh N UN  

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20200227 2


<h4>Objectives</h4>We aimed to study adoption of transradial primary percutaneous coronary intervention (TR-PPCI) for ST elevation myocardial infarction (STEMI) ("radial first" approach) and its association with door-to-balloon time (D2BT).<h4>Background</h4>TR-PPCI for STEMI is underutilized in the United States due to concerns about prolonging D2BT. Whether operators and hospitals adopting a radial first approach in STEMI incur prolonged D2BT is unknown.<h4>Methods</h4>In 1,272 consecutive cas  ...[more]

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