Ontology highlight
ABSTRACT:
SUBMITTER: Mohsen MO
PROVIDER: S-EPMC7496916 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Mohsen Mona O MO Augusto Gilles G Bachmann Martin F MF
Immunological reviews 20200530 1
Vaccines need to be rationally designed in order be delivered to the immune system for maximizing induction of dynamic immune responses. Virus-like particles (VLPs) are ideal platforms for such 3D vaccines, as they allow the display of complex and native antigens in a highly repetitive form on their surface and can easily reach lymphoid organs in intact form for optimal activation of B and T cells. Adjusting size and zeta potential may allow investigators to further fine-tune delivery to lymphoi ...[more]