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Sarcoma of the breast: breast cancer history as etiologic and prognostic factor-A population-based case-control study.


ABSTRACT: PURPOSE:Sarcomas of the breast account for about 1% of all breast malignancies. The aim of this national survey was to explore etiologic and prognostic factors. METHODS:Utilizing national Swedish registers, all patients registered with mesenchymal tumors in the breast during the period 1993-2013 (n?=?344) were identified and compared to up to ten age and gender matched controls. Cancer history was retrieved for cases and controls. Conditional Poisson regression models were used for calculation of odds ratios. RESULTS:Previous breast cancer was overrepresented among patients with angiosarcoma. The highest risk occurred???5 years after treatment for breast cancer (OR 73.9, 95% confidence interval, CI, 25.4-215; P?

SUBMITTER: Karlsson F 

PROVIDER: S-EPMC7497680 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Sarcoma of the breast: breast cancer history as etiologic and prognostic factor-A population-based case-control study.

Karlsson Fredrik F   Granath Fredrik F   Smedby Karin E KE   Zedenius Jan J   Bränström Robert R   Nilsson Inga-Lena IL  

Breast cancer research and treatment 20200721 3


<h4>Purpose</h4>Sarcomas of the breast account for about 1% of all breast malignancies. The aim of this national survey was to explore etiologic and prognostic factors.<h4>Methods</h4>Utilizing national Swedish registers, all patients registered with mesenchymal tumors in the breast during the period 1993-2013 (n = 344) were identified and compared to up to ten age and gender matched controls. Cancer history was retrieved for cases and controls. Conditional Poisson regression models were used fo  ...[more]

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