Dataset Information

Colistin Resistance of Non-pathogenic Strains of Escherichia Coli Occurring as Natural Intestinal Flora in Broiler Chickens Treated and not Treated with Colistin Sulphate.

ABSTRACT: Introduction:A significant threat to public health is presented by antibiotic-resistant strains of bacteria, selective pressure on which results from antibiotic use. Colistin is an antibiotic commonly used in veterinary medicine, but also one of last resort in human medicine. Since the 2015 discovery in China of the mcr-1 gene encoding colistin resistance in Enterobacteriaceae, other countries have noted its presence. This study was to find the mcr-1 gene prevalence in E. coli isolated from poultry slaughtered in Poland. Material and Methods:Cloacal swabs were taken from December 2017 to October 2018 from broiler chickens in three regions. The samples (n = 158) were grouped as flocks treated with colistin sulphate (n = 87) and those not treated (n = 71). Resistance to antimicrobials commonly used in poultry was evaluated by minimum inhibitory concentration. The presence of the mcr-1 gene was confirmed by PCR. Results:Isolates containing the mcr-1 gene were yielded by 11.27% of the samples from not treated flocks and 19.54% of those from treated flocks, but no statistically significant difference in the prevalence of the gene was seen between the groups. Conclusion:The results clearly preclude intensification of selective pressure for colistin resistance due to colistin sulphate treatment because they show that the avian gastrointestinal tract was already inhabited by colistin-resistant E. coli by the time the chickens came to the poultry house.

SUBMITTER: Majewski M

PROVIDER: S-EPMC7497749 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Colistin Resistance of Non-pathogenic Strains of <i>Escherichia Coli</i> Occurring as Natural Intestinal Flora in Broiler Chickens Treated and not Treated with Colistin Sulphate.

Majewski Michał M Łukomska Anna A Wilczyński Jarosław J Wystalska Danuta D Racewicz Przemysław P Nowacka-Woszuk Joanna J Pszczola Marcin M Anusz Krzysztof K

Journal of veterinary research 20200916 3

<h4>Introduction</h4>A significant threat to public health is presented by antibiotic-resistant strains of bacteria, selective pressure on which results from antibiotic use. Colistin is an antibiotic commonly used in veterinary medicine, but also one of last resort in human medicine. Since the 2015 discovery in China of the <i>mcr-1</i> gene encoding colistin resistance in <i>Enterobacteriaceae</i>, other countries have noted its presence. This study was to find the <i>mcr-1</i> gene prevalence ...[more]

PMID: 32984630

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Dataset Information

Colistin Resistance of Non-pathogenic Strains of Escherichia Coli Occurring as Natural Intestinal Flora in Broiler Chickens Treated and not Treated with Colistin Sulphate.

Publications

Colistin Resistance of Non-pathogenic Strains of <i>Escherichia Coli</i> Occurring as Natural Intestinal Flora in Broiler Chickens Treated and not Treated with Colistin Sulphate.

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