Ontology highlight
ABSTRACT:
SUBMITTER: Quarton T
PROVIDER: S-EPMC7498316 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Quarton Tyler T Kang Taek T Papakis Vasileios V Nguyen Khai K Nowak Chance C Li Yi Y Bleris Leonidas L
Nucleic acids research 20200901 16
Eukaryotic protein synthesis is an inherently stochastic process. This stochasticity stems not only from variations in cell content between cells but also from thermodynamic fluctuations in a single cell. Ultimately, these inherently stochastic processes manifest as noise in gene expression, where even genetically identical cells in the same environment exhibit variation in their protein abundances. In order to elucidate the underlying sources that contribute to gene expression noise, we quantif ...[more]