Outcomes in infants < 29 weeks of gestation following single-dose prophylactic indomethacin.
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ABSTRACT:
SUBMITTER: Gillam-Krakauer M
PROVIDER: S-EPMC7499931 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
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Outcomes in infants < 29 weeks of gestation following single-dose prophylactic indomethacin.
Gillam-Krakauer Maria M Slaughter James C JC Cotton Robert B RB Robinson Blaine E BE Reese Jeff J Maitre Nathalie L NL
Journal of perinatology : official journal of the California Perinatal Association 20200918 1
<h4>Background</h4>Prophylactic indomethacin (3 doses) decreases patent ductus arteriosus (PDA) and intraventricular hemorrhage (IVH) in preterm infants. The study aim was to determine whether single-dose indomethacin (SD-INDO) decreases PDA, IVH, and improves motor function.<h4>Methods</h4>A retrospective cohort (2007-2014) compared infants born < 29 weeks who did (n = 299) or did not (n = 85) receive SD-INDO and estimated outcomes association with ordinal logistic regression, adjusting for mul ...[more]
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