Ontology highlight
ABSTRACT:
SUBMITTER: Dettweiler M
PROVIDER: S-EPMC7501240 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Dettweiler Micah M Marquez Lewis L Lin Michelle M Sweeney-Jones Anne M AM Chhetri Bhuwan Khatri BK Zurawski Daniel V DV Kubanek Julia J Quave Cassandra L CL
Scientific reports 20200918 1
The rise of antibiotic resistance has necessitated a search for new antimicrobials with potent activity against multidrug-resistant gram-negative pathogens, such as carbapenem-resistant Acinetobacter baumannii (CRAB). In this study, a library of botanical extracts generated from plants used to treat infections in traditional medicine was screened for growth inhibition of CRAB. A crude extract of Schinus terebinthifolia leaves exhibited 80% inhibition at 256 µg/mL and underwent bioassay-guided fr ...[more]