Ontology highlight
ABSTRACT:
SUBMITTER: Wohlers I
PROVIDER: S-EPMC7501257 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Wohlers Inken I Künstner Axel A Munz Matthias M Olbrich Michael M Fähnrich Anke A Calonga-Solís Verónica V Ma Caixia C Hirose Misa M El-Mosallamy Shaaban S Salama Mohamed M Busch Hauke H Ibrahim Saleh S
Nature communications 20200918 1
A small number of de novo assembled human genomes have been reported to date, and few have been complemented with population-based genetic variation, which is particularly important for North Africa, a region underrepresented in current genome-wide references. Here, we combine long- and short-read whole-genome sequencing data with recent assembly approaches into a de novo assembly of an Egyptian genome. The assembly demonstrates well-balanced quality metrics and is complemented with variant phas ...[more]