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Vaccines for COVID-19: perspectives from nucleic acid vaccines to BCG as delivery vector system.


ABSTRACT: This article discusses standard and new disruptive strategies in the race to develop an anti-COVID-19 vaccine. We also included new bioinformatic data from our group mapping immunodominant epitopes and structural analysis of the spike protein. Another innovative approach reviewed here is the use of BCG vaccine as priming strategy and/or delivery system expressing SARS-CoV-2 antigens.

SUBMITTER: de Queiroz NMGP 

PROVIDER: S-EPMC7501874 | biostudies-literature | 2020 Nov - Dec

REPOSITORIES: biostudies-literature

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Vaccines for COVID-19: perspectives from nucleic acid vaccines to BCG as delivery vector system.

de Queiroz Nina Marí G P NMGP   Marinho Fabio V FV   Chagas Marcelo A MA   Leite Luciana C C LCC   Homan E Jane EJ   de Magalhães Mariana T Q MTQ   Oliveira Sergio C SC  

Microbes and infection 20200919 10


This article discusses standard and new disruptive strategies in the race to develop an anti-COVID-19 vaccine. We also included new bioinformatic data from our group mapping immunodominant epitopes and structural analysis of the spike protein. Another innovative approach reviewed here is the use of BCG vaccine as priming strategy and/or delivery system expressing SARS-CoV-2 antigens. ...[more]

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