Association of Serum Renalase Levels and Renalase rs10887800 Polymorphism with Unstable Angina Pectoris Patients Having Metabolic Syndrome.

ABSTRACT:

Purpose

An increased risk of cardiovascular mortality and morbidity has been linked with metabolic syndrome (MetS), described as the secondary risk reduction target. These patients are predisposed to high complication levels such as unstable angina-pectoris (USAP) by MetS. As with the role of renalase in the regulation of blood pressure (BP), the study was carried out to determine the levels of renalase circulation in patients with USAP and MetS (USAP+MetS), as well as the association of renalase gene (RNLS) rs10887800 polymorphism and USAP and MetS susceptibility.

Patients and methods

A total of 134 patients with USAP+MetS and 134 control subjects were recruited in this case-control study.

Results

Renalase was found to have a significantly higher level in USAP

SUBMITTER: Izadpanah P 

PROVIDER: S-EPMC7501982 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature