Type 2 diabetes is an independent predictor of lowered peak aerobic capacity in heart failure patients with non-reduced or reduced left ventricular ejection fraction.
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ABSTRACT:
SUBMITTER: Abe T
PROVIDER: S-EPMC7502205 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
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Type 2 diabetes is an independent predictor of lowered peak aerobic capacity in heart failure patients with non-reduced or reduced left ventricular ejection fraction.
Abe Takahiro T Yokota Takashi T Fukushima Arata A Kakutani Naoya N Katayama Takashi T Shirakawa Ryosuke R Maekawa Satoshi S Nambu Hideo H Obata Yoshikuni Y Yamanashi Katsuma K Nakano Ippei I Takada Shingo S Yokota Isao I Okita Koichi K Kinugawa Shintaro S Anzai Toshihisa T
Cardiovascular diabetology 20200919 1
<h4>Background</h4>Although type 2 diabetes mellitus (T2DM) is one of the most frequent comorbidities in patients with chronic heart failure (CHF), the effects of T2DM on the exercise capacity of CHF patients are fully unknown. Here, we tested the hypothesis that the coexistence of T2DM lowers CHF patients' peak aerobic capacity.<h4>Methods</h4>We retrospectively analyzed the cases of 275 Japanese CHF patients with non-reduced ejection fraction (left ventricular ejection fraction [LVEF] ≥ 40%) o ...[more]
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