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Patients With Lung Cancer Have High Susceptibility of COVID-19: A Retrospective Study in Wuhan, China.


ABSTRACT: Patients with lung cancer are presumed to be at high risk from COVID-19 infection due to underlying malignancy. A total of 31 COVID-19 patients with pre-diagnosed lung cancer and 186 age and sex matched COVID-19 patients without cancer in 6 hospitals in Wuhan, China were identified in our study. There was a significantly higher level of IL-6 in lung cancer group showed by multifactorial analysis. The restricted mean survival time in 10, 20, and 53 days in COVID-19 patients with lung cancer were ealier than non-cancer COVID-19 patients in the same observation time (all P values < 0.05). Our results indicated that pre-diagnosed lung cancer was associated with higher morbidity and mortality in COVID-19 patients.

SUBMITTER: Dai MY 

PROVIDER: S-EPMC7503035 | biostudies-literature | 2020 Jan-Dec

REPOSITORIES: biostudies-literature

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Patients With Lung Cancer Have High Susceptibility of COVID-19: A Retrospective Study in Wuhan, China.

Dai Meng-Yuan MY   Chen Zhen Z   Leng Yan Y   Wu Meng M   Liu Yu Y   Zhou Fuxiang F   Ming Chen C   Shao Ningyi N   Liu Miao M   Cai Hongbing H  

Cancer control : journal of the Moffitt Cancer Center 20200101 1


Patients with lung cancer are presumed to be at high risk from COVID-19 infection due to underlying malignancy. A total of 31 COVID-19 patients with pre-diagnosed lung cancer and 186 age and sex matched COVID-19 patients without cancer in 6 hospitals in Wuhan, China were identified in our study. There was a significantly higher level of IL-6 in lung cancer group showed by multifactorial analysis. The restricted mean survival time in 10, 20, and 53 days in COVID-19 patients with lung cancer were  ...[more]

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