Ontology highlight
ABSTRACT:
SUBMITTER: Piezzo M
PROVIDER: S-EPMC7503849 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Piezzo Michela M Chiodini Paolo P Riemma Maria M Cocco Stefania S Caputo Roberta R Cianniello Daniela D Di Gioia Germira G Di Lauro Vincenzo V Rella Francesca Di FD Fusco Giuseppina G Iodice Giovanni G Nuzzo Francesco F Pacilio Carmen C Pensabene Matilde M De Laurentiis Michelino M
International journal of molecular sciences 20200903 17
The introduction of CDK4/6 inhibitors in combination with endocrine therapy (ET) represents the most relevant advance in the management of hormone receptor (HR) positive, HER2-negative metastatic breast cancer over the last few years. This meta-analysis of randomized controlled trials (RCTs) is aimed to better characterize the efficacy of CDK4/6 inhibitors in some relevant subgroups and to test heterogeneity between different compounds with a particular focus on their ability to improve overall ...[more]