Ontology highlight
ABSTRACT:
SUBMITTER: Shiromizu T
PROVIDER: S-EPMC7504095 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Shiromizu Takashi T Yuge Mizuki M Kasahara Kousuke K Yamakawa Daishi D Matsui Takaaki T Bessho Yasumasa Y Inagaki Masaki M Nishimura Yuhei Y
International journal of molecular sciences 20200819 17
Cilia are antenna-like structures present in many vertebrate cells. These organelles detect extracellular cues, transduce signals into the cell, and play an essential role in ensuring correct cell proliferation, migration, and differentiation in a spatiotemporal manner. Not surprisingly, dysregulation of cilia can cause various diseases, including cancer and ciliopathies, which are complex disorders caused by mutations in genes regulating ciliary function. The structure and function of cilia are ...[more]