Interaction between Immunotherapy and Antiangiogenic Therapy for Cancer.
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ABSTRACT:
SUBMITTER: Furukawa K
PROVIDER: S-EPMC7504110 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Publications
Interaction between Immunotherapy and Antiangiogenic Therapy for Cancer.
Furukawa Koichi K Nagano Tatsuya T Tachihara Motoko M Yamamoto Masatsugu M Nishimura Yoshihiro Y
Molecules (Basel, Switzerland) 20200826 17
Although immunotherapy has led to durable responses in diverse cancers, unfortunately, there has been limited efficacy and clinical response rates due to primary or acquired resistance to immunotherapy. To maximize the potential of immunotherapy, combination therapy with antiangiogenic drugs seems to be promising. Some phase III trials showed superiority for survival with the combination of immunotherapy and antiangiogenic therapy. In this study, we describe a synergistic mechanism of immunother ...[more]
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