Ontology highlight
ABSTRACT:
SUBMITTER: Ruan J
PROVIDER: S-EPMC7504330 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Ruan Jingya J Zhang Ying Y Zhao Wei W Sun Fan F Han Lifeng L Yu Haiyang H Wu Lijie L Zhang Yi Y Wang Tao T
Molecules (Basel, Switzerland) 20200820 17
Two new 12,23-epoxydammarane-type saponins, notoginsenosides NL-I (<b>1</b>) and NL-J (<b>2</b>), were isolated and identified from <i>Panax notoginseng</i> leaves through the combination of various chromatographies and extensive spectroscopic methods, as well as chemical reactions. Among them, notoginsenoside NL-J (<b>2</b>) had a new skeleton. Furthermore, the lipopolysaccharide (LPS)-induced RAW 264.7 macrophage model was used to identify the in vitro anti-inflammatory activity and mechanisms ...[more]