Ontology highlight
ABSTRACT:
SUBMITTER: Houghton V
PROVIDER: S-EPMC7505931 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Houghton Vikki V Du Preez Andrea A Lefèvre-Arbogast Sophie S de Lucia Chiara C Low Dorrain Y DY Urpi-Sarda Mireia M Ruigrok Silvie R SR Altendorfer Barbara B González-Domínguez Raúl R Andres-Lacueva Cristina C Aigner Ludwig L Lucassen Paul J PJ Korosi Aniko A Samieri Cécilia C Manach Claudine C Thuret Sandrine S
Frontiers in cell and developmental biology 20200908
The age-associated reduction in the proliferation of neural stem cells (NSCs) has been associated with cognitive decline. Numerous factors have been shown to modulate this process, including dietary components. Frequent consumption of caffeine has been correlated with an increased risk of cognitive decline, but further evidence of a negative effect on hippocampal progenitor proliferation is limited to animal models. Here, we used a human hippocampal progenitor cell line to investigate the effect ...[more]