Ontology highlight
ABSTRACT:
SUBMITTER: Jiang Y
PROVIDER: S-EPMC7506152 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in oncology 20200908
<h4>Background</h4>Serum sphingolipids are widely involved in the development of hepatocellular carcinoma (HCC). We investigated the serum sphingolipid profile in patients with HCC or cirrhosis and explored the potential diagnostic efficiency of serum sphingolipid metabolites which may be helpful in differentiating HCC including α-fetoprotein (AFP)-negative HCC from cirrhosis.<h4>Methods</h4>Seventy-two HCC patients (including 24 AFP-negative HCC) and 104 cirrhotic patients were consecutively en ...[more]