Ontology highlight
ABSTRACT:
SUBMITTER: Chin HG
PROVIDER: S-EPMC7507628 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Chin Hang Gyeong HG Sun Zhiyi Z Vishnu Udayakumar S US Hao Pengying P Cejas Paloma P Spracklin George G Estève Pierre-Olivier PO Xu Shuang-Yong SY Long Henry W HW Pradhan Sriharsa S
Clinical epigenetics 20200922 1
Accessible chromatin plays a central role in gene expression and chromatin architecture. Current accessible chromatin approaches depend on limited digestion/cutting and pasting adaptors at the accessible DNA, thus requiring additional materials and time for optimization. Universal NicE-seq (UniNicE-seq) is an improved accessible chromatin profiling method that negates the optimization step and is suited to a variety of mammalian cells and tissues. Addition of 5-methyldeoxycytidine triphosphate d ...[more]