Ontology highlight
ABSTRACT:
SUBMITTER: Lindholm H
PROVIDER: S-EPMC7507731 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Lindholm Heléne H Morrison India I Krettek Alexandra A Malm Dan D Novembre Giovanni G Handlin Linda L
BMC medical genetics 20200921 1
<h4>Background</h4>Two important aspects for the development of anxiety disorders are genetic predisposition and alterations in the hypothalamic-pituitary-adrenal (HPA) axis. In order to identify genetic risk-factors for anxiety, the aim of this exploratory study was to investigate possible relationships between genetic polymorphisms in genes important for the regulation and activity of the HPA axis and self-assessed anxiety in healthy individuals.<h4>Methods</h4>DNA from 72 healthy participants ...[more]