Ontology highlight
ABSTRACT:
SUBMITTER: Zhu W
PROVIDER: S-EPMC7507806 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Zhu Wei W Xu Miao M Chen Catherine Z CZ Guo Hui H Shen Min M Hu Xin X Shinn Paul P Klumpp-Thomas Carleen C Michael Samuel G SG Zheng Wei W
ACS pharmacology & translational science 20200904 5
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emphasized the urgency to develop effective therapeutics. Drug repurposing screening is regarded as one of the most practical and rapid approaches for the discovery of such therapeutics. The 3C-like protease (3CL<sup>pro</sup>), or main protease (M<sup>pro</sup>) of SARS-CoV-2 is a valid drug target as it is a specific viral enzyme and plays an essential role in viral re ...[more]