Ontology highlight
ABSTRACT:
SUBMITTER: Gorman SD
PROVIDER: S-EPMC7508002 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Gorman Scott D SD D'Amico Rebecca N RN Winston Dennis S DS Boehr David D DD
Advances in experimental medicine and biology 20190101
Our ability to engineer protein structure and function has grown dramatically over recent years. Perhaps the next level in protein design is to develop proteins whose function can be regulated in response to various stimuli, including ligand binding, pH changes, and light. Endeavors toward these goals have tested and expanded on our understanding of protein function and allosteric regulation. In this chapter, we provide examples from different methods for developing new allosterically regulated ...[more]