Ontology highlight
ABSTRACT:
SUBMITTER: Haider V
PROVIDER: S-EPMC7508174 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Haider Victoria V Kreuzer Viktoria V Tiffner Maximilian M Spingler Bernhard B Waser Mario M
European journal of organic chemistry 20200715 32
We herein report an ammonium salt-catalyzed protocol for the regioselective ring opening of aryl-aziridines with β-keto esters. The reaction gives access to a variety of highly functionalized target molecules with two consecutive stereo-genic centers and can be rendered enantioselective (up to <i>e.r.</i> = 91:9) by using bifunctional chiral ammonium salt catalysts. ...[more]