Ontology highlight
ABSTRACT:
SUBMITTER: Liu R
PROVIDER: S-EPMC7508552 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Liu Ran R Greenstein Joseph L JL Fackler James C JC Bembea Melania M MM Winslow Raimond L RL
eLife 20200922
Sepsis is not a monolithic disease, but a loose collection of symptoms with diverse outcomes. Thus, stratification and subtyping of sepsis patients is of great importance. We examine the temporal evolution of patient state using our previously-published method for computing risk of transition from sepsis into septic shock. Risk trajectories diverge into four clusters following early prediction of septic shock, stratifying by outcome: the highest-risk and lowest-risk groups have a 76.5% and 10.4% ...[more]