Ontology highlight
ABSTRACT:
SUBMITTER: Du Z
PROVIDER: S-EPMC7511324 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Du Zhenhua Z Liu Xinyi X Wei Xiaojun X Luo Hongbo H Li Peiyao P Shi Mengting M Guo Bingqian B Cui Ying Y Su Zhenglin Z Zeng Jifeng J Si Anfeng A Cao Pengbo P Zhou Gangqiao G
Scientific reports 20200923 1
More efficient biomarkers are needed to facilitate the early detection of hepatocellular carcinoma (HCC). We aimed to identify candidate biomarkers for HCC detection by proteomic analysis. First, we performed a global proteomic analysis of 10 paired HCC and non-tumor tissues. Then, we validated the top-ranked proteins by targeted proteomic analyses in another tissue cohort. At last, we used enzyme-linked immunosorbent assays to validate the candidate biomarkers in multiple serum cohorts includin ...[more]