Ontology highlight
ABSTRACT:
SUBMITTER: Pattanayak B
PROVIDER: S-EPMC7511588 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Pattanayak Birlipta B Garrido-Cano Iris I Adam-Artigues Anna A Tormo Eduardo E Pineda Begoña B Cabello Paula P Alonso Elisa E Bermejo Begoña B Hernando Cristina C Martínez María Teresa MT Rovira Ana A Albanell Joan J Rojo Federico F Burgués Octavio O Cejalvo Juan Miguel JM Lluch Ana A Eroles Pilar P
Frontiers in oncology 20200910
Downregulation of miR-33b has been documented in many types of cancers and is being involved in proliferation, migration, and epithelial-mesenchymal transition (EMT). Furthermore, the enhancer of zeste homolog 2-gene (EZH2) is a master regulator of controlling the stem cell differentiation and the cell proliferation processes. We aim to evaluate the implication of miR-33b in the EMT pathway in HER2+ breast cancer (BC) and to analyze the role of EZH2 in this process as well as the interaction bet ...[more]