Ontology highlight
ABSTRACT:
SUBMITTER: Wang XF
PROVIDER: S-EPMC7513859 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Wang Xiao-Fei XF Xie Shi-Ming SM Guo Shi-Meng SM Su Ping P Zhou Li-Quan LQ
Cell cycle (Georgetown, Tex.) 20200814 17
After fertilization, highly differentiated sperm and oocyte are reprogrammed to totipotent embryo, which subsequently cleavages and develops into an individual through spatial-temporal differentiation. Histone modifications play critical roles to coordinate with other reprogramming events in early stages of embryogenesis. However, most of studies focus on modifications at N-terminus of histones, those at nucleosome core were not well understood. Here, we characterize the three key acetylation ev ...[more]