Ontology highlight
ABSTRACT:
SUBMITTER: Jeffries NO
PROVIDER: S-EPMC7515605 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Jeffries Neal O NO Troendle James F JF Geller Nancy L NL
Biometrics 20171218 3
In longitudinal studies comparing two treatments over a series of common follow-up measurements, there may be interest in determining if there is a treatment difference at any follow-up period when there may be a non-monotone treatment effect over time. To evaluate this question, Jeffries and Geller (2015) examined a number of clinical trial designs that allowed adaptive choice of the follow-up time exhibiting the greatest evidence of treatment difference in a group sequential testing setting wi ...[more]