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ABSTRACT: Objectives
To review molecular diagnostics for coronavirus disease 2019. The world is in the midst of a coronavirus disease 2019 pandemic. Containing the spread of the severe acute respiratory distress coronavirus is critical. Instrumental to the future success is the ability to reliably and reproducibly detect this inciting pathogen to inform public health containment policies and treatment decisions.Data sources
Molecular diagnostics focusing on molecular detection methodologies for detection of the virus and the presence of the disease.Study selection
Narrative review.Data extraction
Literature, PubMed, Scopus, and official government documents.Data synthesis
Diagnosing severe acute respiratory syndrome coronavirus is done through real-time reverse transcriptase-polymerase chain reaction tests, cell culture, and serology. For patients, diagnostics are an integral part of a full medical history, physical examinations, blood tests, and diagnostic imaging.Conclusions
Here, we review current approaches to the molecular diagnosis of coronavirus disease 2019.
SUBMITTER: Dos Santos CC
PROVIDER: S-EPMC7515613 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Dos Santos Claudia C CC Zehnbauer Barbara A BA Trahtemberg Uriel U Marshall John J
Critical care explorations 20200917 9
<h4>Objectives</h4>To review molecular diagnostics for coronavirus disease 2019. The world is in the midst of a coronavirus disease 2019 pandemic. Containing the spread of the severe acute respiratory distress coronavirus is critical. Instrumental to the future success is the ability to reliably and reproducibly detect this inciting pathogen to inform public health containment policies and treatment decisions.<h4>Data sources</h4>Molecular diagnostics focusing on molecular detection methodologie ...[more]