Ontology highlight
ABSTRACT:
SUBMITTER: Delgado-Balderas JR
PROVIDER: S-EPMC7517572 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Delgado-Balderas Jesus Rolando JR Gallardo-Blanco Hugo Leonid HL Yee-De León Juan Felipe JF Rivas-Estilla Ana Maria AM Soto-García Brenda B Aráiz-Hernández Diana D Garza-Guajardo Raquel R Náñez-Marín Melissa M Hernández-Barajas David D García-Bailón Aldo Missael AM Vízcarra-Mata Guillermo G Ocaña-Munguía Marco Alberto MA Gómez-Guerra Lauro Salvador LS Sánchez-Domínguez Celia Nohemí CN
Oncology letters 20200918 5
The presence of the genetic variants of the steroid 5-alpha reductase 2 enzyme, which is encoded by the <i>SRD5A2</i> gene, has been associated with an increased risk of developing prostate cancer among certain ethnic groups. However, these molecular studies have not been conducted on the Mexican population. The analysis of the genetic variants, rs9282858 and rs523349, was performed in 101 males with prostate cancer and 100 healthy controls classified as males without prostate abnormalities (n=6 ...[more]