Tuning the porosity of biofabricated chitosan membranes in microfluidics with co-assembled nanoparticles as templates.

ABSTRACT: Biopolymer membranes assembled in microfluidic devices offer many biological process- and analysis-related applications. One of the key characteristics of bio-fabricated membranes is their porosity, which regulates the transport of molecules, ions, or particles and contributes to their semi-permeability and selectivity. This study aims to tune the porosity of biofabricated chitosan membranes (CM) using incorporated nanoparticles as templates. CM with polystyrene nanoparticles (CM-np) were assembled by flow in microchannel networks. The membranes with incorporated nanoparticles were crosslinked with glutaraldehyde, and then the nanoparticles were dissolved with dimethyl sulfoxide. The in situ synthesized porous CM (pCM) were characterized with scanning electron microscopy and polariz

SUBMITTER: Ly KL 

PROVIDER: S-EPMC7518516 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature