Inflammatory Biomarkers Do Not Differ Between Persistently Seronegative vs Seropositive People With HIV After Treatment in Early Acute HIV Infection.
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ABSTRACT:
SUBMITTER: Cai CW
PROVIDER: S-EPMC7519777 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
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Inflammatory Biomarkers Do Not Differ Between Persistently Seronegative vs Seropositive People With HIV After Treatment in Early Acute HIV Infection.
Cai Catherine W CW Pinyakorn Suteeraporn S Kroon Eugène E de Souza Mark M Colby Donn J DJ Pankam Tippawan T Pattanachaiwit Supanit S Ubolyam Sasiwimol S Rupert Adam A Lallemand Perrine P Dewar Robin R Highbarger Helene C HC Ananworanich Jintanat J Vasan Sandhya S Sereti Irini I
Open forum infectious diseases 20200826 9
Persistent viral activity may cause enduring seropositivity and inflammation in treated people with HIV (PWH). We compared inflammatory biomarkers between early treated PWH who remained seronegative or seroconverted and found similar levels of D-dimer, soluble cluster of differentiation 14, C-reactive protein, and interleukin-6, indicating that seronegativity does not affect chronic inflammation in early treated PWH. ...[more]
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