Ontology highlight
ABSTRACT:
SUBMITTER: Wang R
PROVIDER: S-EPMC7523113 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Wang Ruofan R Simoneau Camille R CR Kulsuptrakul Jessie J Bouhaddou Mehdi M Travisano Katherine K Hayashi Jennifer M JM Carlson-Stevermer Jared J Oki Jennifer J Holden Kevin K Krogan Nevan J NJ Ott Melanie M Puschnik Andreas S AS
bioRxiv : the preprint server for biology 20200924
The <i>Coronaviridae</i> are a family of viruses that causes disease in humans ranging from mild respiratory infection to potentially lethal acute respiratory distress syndrome. Finding host factors that are common to multiple coronaviruses could facilitate the development of therapies to combat current and future coronavirus pandemics. Here, we conducted parallel genome-wide CRISPR screens in cells infected by SARS-CoV-2 as well as two seasonally circulating common cold coronaviruses, OC43 and ...[more]