Ontology highlight
ABSTRACT:
SUBMITTER: Motoki H
PROVIDER: S-EPMC7524086 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Motoki Hirohiko H Masuda Izuru I Yasuno Shinji S Oba Koji K Shoin Wataru W Usami Satoru S Saito Yoshihiko Y Waki Masako M Komatsu Mitsuhisa M Ueshima Kenji K Nakagawa Yasuaki Y Son Cheol C Yonemitsu Shin S Hiramitsu Shinya S Konda Manako M Onishi Katsuya K Kuwahara Koichiro K
ESC heart failure 20200623 5
<h4>Aims</h4>A sodium glucose cotransporter 2 (SGLT2) inhibitor was recently found to reduce heart failure hospitalization in the EMPA-REG OUTCOME trial. We have hypothesized that autonomic nerve activity may be modulated by SGLT2 inhibition. The current study aims to investigate the impact of empagliflozin on sympathetic and parasympathetic nerve activity in patients with type 2 diabetes mellitus.<h4>Methods and results</h4>This ongoing study is a prospective, randomized, open-label, multicentr ...[more]