Mechanotransduction of stem cells for tendon repair.
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ABSTRACT:
SUBMITTER: Wang HN
PROVIDER: S-EPMC7524696 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Publications
Mechanotransduction of stem cells for tendon repair.
Wang Hao-Nan HN Huang Yong-Can YC Ni Guo-Xin GX
World journal of stem cells 20200901 9
Tendon is a mechanosensitive tissue that transmits force from muscle to bone. Physiological loading contributes to maintaining the homeostasis and adaptation of tendon, but aberrant loading may lead to injury or failed repair. It is shown that stem cells respond to mechanical loading and play an essential role in both acute and chronic injuries, as well as in tendon repair. In the process of mechanotransduction, mechanical loading is detected by mechanosensors that regulate cell differentiation ...[more]
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