Dataset Information

Evaluation of Polyethylene Surgical Drape as an Alternative Wound Dressing Material, Compared to Banana Leaf (Musa paradisiaca) Dressing in Facial Abrasions.

ABSTRACT:

Background and objectives

Facial abrasions, the most common squeal of trauma, have been treated widely by moist occlusive dressings. This novel study aims to evaluate polyethylene surgical drape dressing (PESG) as an alternative to autoclaved banana leaf (Musa paradisiaca) dressing in facial abrasions.

Study design

Sixty patients who reported to our emergency department, having abrasions over head, neck and face region secondary to trauma, were included. Thirty patients were given PESG, and 30 were given banana leaf dressings. Dressings were changed daily for 7 days. Pain on dressing change, status of wound bed on every dressing change, handling characteristics of each dressing material and comfort to the patient were assessed.

Results

Analysis revealed that the properties of PESG dressings are parallel to banana leaf dressing in all aspects except pain on dressing change. PESG caused no pain during dressing change which was statistically significant (p < 0.011).

Conclusion

Facial abrasions can be effectively treated by PESG dressing. It is easily available in any hospital setting, has an ideal surface, i.e. impervious and smooth. It also maintains a moist condition, is completely painless and inexpensive. Hence, it can become a new standard for treating facial abrasions especially to poor patients in developing countries.

SUBMITTER: Mulukutla S

PROVIDER: S-EPMC7524904 | biostudies-literature |

REPOSITORIES: biostudies-literature

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Project description:Secondary metabolites and their biological activity have pharmacological relevance in the prevention and therapeutic management of disease, including the facilitation of normal physiological processes through biochemical mechanisms. In this study, phytochemical constituents and antioxidant activity were evaluated quantitatively on the acetone, ethanol, and aqueous extracts of the flesh, and peel, as well as the boiled peel extract compartments of Musa sinensis L. and Musa paradisiaca L. fruits. Total phenol, proanthocyanidin, and flavonoid contents were estimated and measured spectrophotometrically. The free radical scavenging antioxidant capacity of the extracts was tested on DPPH (2,2-diphenyl-1-picrylhydrazyl ethanol), ABTS (2,2?-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid)), and FRAP (ferric reducing antioxidant power) assay models. Correlation between phytoconstituents and antioxidant activity was analysed using Pearson's coefficient. The results showed varying amounts of phytochemicals in the solvent extracts of the flesh and peel, including the boiled peel extract of M. sinensis and M. paradisiaca. All acetone extracts of M. sinensis flesh, M. paradisiaca flesh, and M. paradisiaca peel had the highest phytochemical contents, with the exception of the ethanol extract of M. sinensis peel which had the highest phenol content; just as on the overall scale, the peel compartments had generally higher phytochemical profiles than the soft flesh in both fruits. The boiled peel extracts of M. sinensis and M. paradisiaca had the highest ABTS (0.03?mg/mL) and DPPH (0.03?mg/mL) activity. Ferric reducing power (FRAP) was the highest in the ethanol extracts of M. sinensis flesh and peel, and M. paradisiaca flesh, while it was the highest in the acetone extract of M. paradisiaca at the peak concentration used (0.1?mg/mL). There was a significant negative correlation between the total phenol and flavonoid contents of M. sinensis flesh with its DPPH radical scavenging activity and proanthocyanidin content of M. paradisiaca flesh with its DPPH radical scavenging activity. The correlation outcomes indicate that none of the phytochemical constituents solely affected antioxidant activity; instead, a combination of the polyphenolic constituents contributed to antioxidant activity. This study shows the therapeutic potentials of the flesh and, importantly, the peel of M. sinensis and M. paradisiaca fruits on the basis of the polyphenolic constitution against free radicals and oxidative stress.