Dataset Information

SF-12 or SF-36 in pituitary disease? Toward concise and comprehensive patient-reported outcomes measurements.

ABSTRACT:

Purpose

Pituitary diseases severely affect patients' health-related quality of life (HRQoL). The most frequently used generic HRQoL questionnaire is the Short Form-36 (SF-36). The shorter 12-item version (SF-12) can improve efficiency of patient monitoring. This study aimed to determine whether SF-12 can replace SF-36 in pituitary care.

Methods

In a longitudinal cohort study (August 2016 to December 2018) among 103 endoscopically operated adult pituitary tumor patients, physical and mental component scores (PCS and MCS) of SF-36 and SF-12 were measured preoperatively, and 6 weeks and 6 months postoperatively. Chronic care was assessed with a cross-sectional study (N?=?431). Mean differences and agreement between SF-36 and SF-12 change in scores (preoperative vs. 6 months) were assessed with intraclass correlation coefficients (ICC) and limits of agreement, depicting 95% of individual patients.

Results

In the longitudinal study, mean differences between change in SF-36 and SF-12 scores were 1.4 (PCS) and 0.4 (MCS) with fair agreement for PCS (ICC?=?0.546) and substantial agreement for MCS (ICC?=?0.931). For 95% of individual patients, the difference between change in SF-36 and SF-12 scores varied between -14.0 and 16.9 for PCS and between -7.8 and 8.7 for MCS. Cross-sectional results showed fair agreement for PCS (ICC?=?0.597) and substantial agreement for MCS (ICC?=?0.943).

Conclusions

On a group level, SF-12 can reliably reproduce MCS in pituitary patients, although PCS is less well correlated. However, individual differences between SF-36 and SF-12 can be large. For pituitary diseases, alternative strategies are needed for concise, but comprehensive patient-reported outcome measurement.

SUBMITTER: van der Meulen M

PROVIDER: S-EPMC7525280 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Publications

SF-12 or SF-36 in pituitary disease? Toward concise and comprehensive patient-reported outcomes measurements.

van der Meulen Merel M Zamanipoor Najafabadi Amir H AH Lobatto Daniel J DJ Andela Cornelie D CD Vliet Vlieland Thea P M TPM Pereira Alberto M AM van Furth Wouter R WR Biermasz Nienke R NR

Endocrine 20200619 1

<h4>Purpose</h4>Pituitary diseases severely affect patients' health-related quality of life (HRQoL). The most frequently used generic HRQoL questionnaire is the Short Form-36 (SF-36). The shorter 12-item version (SF-12) can improve efficiency of patient monitoring. This study aimed to determine whether SF-12 can replace SF-36 in pituitary care.<h4>Methods</h4>In a longitudinal cohort study (August 2016 to December 2018) among 103 endoscopically operated adult pituitary tumor patients, physical a ...[more]

PMID: 32562182

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Dataset Information

SF-12 or SF-36 in pituitary disease? Toward concise and comprehensive patient-reported outcomes measurements.

Purpose

Methods

Results

Conclusions

Publications

SF-12 or SF-36 in pituitary disease? Toward concise and comprehensive patient-reported outcomes measurements.

Similar Datasets

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