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Longitudinal adrenal gland measurements and growth trajectories as risk markers for late preterm delivery.


ABSTRACT: BACKGROUND:The fetal adrenal gland receives rising awareness as a predictor of spontaneous preterm birth. We hereby provide longitudinal growth assessments of the fetal adrenal gland in a low risk population with an additional focus on trajectories in fetuses born preterm. METHODS:Fetal adrenal gland was assessed via transabdominal ultrasound at gestational weeks (gw) 24-26, 28-30, and 34-36 in a low-risk pregnancy cohort. Longitudinal trajectories of the total gland and the mark (so called fetal zone) as well as ratio of fetal zone width/ total widths (w/W) were analyzed using repeated ANOVA analyses. To compare trajectories of the ratio w/W for preterm and term fetuses respectively, as well as women with and without clinical signs of preterm labor, the propensity score method was applied. RESULTS:Fetal zone width increased over the course of pregnancy (p?

SUBMITTER: Goletzke J 

PROVIDER: S-EPMC7526396 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Longitudinal adrenal gland measurements and growth trajectories as risk markers for late preterm delivery.

Goletzke Janina J   Pagenkemper Mirja M   Wiessner Christian C   Rüber Franziska F   Arck Petra P   Hecher Kurt K   Diemert Anke A  

BMC pregnancy and childbirth 20200929 1


<h4>Background</h4>The fetal adrenal gland receives rising awareness as a predictor of spontaneous preterm birth. We hereby provide longitudinal growth assessments of the fetal adrenal gland in a low risk population with an additional focus on trajectories in fetuses born preterm.<h4>Methods</h4>Fetal adrenal gland was assessed via transabdominal ultrasound at gestational weeks (gw) 24-26, 28-30, and 34-36 in a low-risk pregnancy cohort. Longitudinal trajectories of the total gland and the mark  ...[more]

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