Criteria for defining interictal epileptiform discharges in EEG: A clinical validation study.

ABSTRACT:

Objective

To define and validate criteria for accurate identification of EEG interictal epileptiform discharges (IEDs) using (1) the 6 sensor space criteria proposed by the International Federation of Clinical Neurophysiology (IFCN) and (2) a novel source space method. Criteria yielding high specificity are needed because EEG over-reading is a common cause of epilepsy misdiagnosis.

Methods

Seven raters reviewed EEG sharp transients from 100 patients with and without epilepsy (diagnosed definitively by video-EEG recording of habitual events). Raters reviewed the transients, randomized, and classified them as epileptiform or nonepileptiform in 3 separate rounds: in 2, EEG was reviewed in sensor space (scoring the presence/absence of each IFCN criterion for each transient or cl

SUBMITTER: Kural MA 

PROVIDER: S-EPMC7526669 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature