Ontology highlight
ABSTRACT:
SUBMITTER: Garcia-Castano A
PROVIDER: S-EPMC7527205 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
García-Castaño Alejandro A Madariaga Leire L Antón-Gamero Montserrat M Mejia Natalia N Ponce Jenny J Gómez-Conde Sara S Pérez de Nanclares Gustavo G De la Hoz Ana Belén AB Martínez Rosa R Saso Laura L Martínez de LaPiscina Idoia I Urrutia Inés I Velasco Olaia O Aguayo Aníbal A Castaño Luis L Gaztambide Sonia S
PloS one 20200930 9
The maintenance of magnesium (Mg2+) homeostasis is essential for human life. The Cystathionine-β-synthase (CBS)-pair domain divalent metal cation transport mediators (CNNMs) have been described to be involved in maintaining Mg2+ homeostasis. Among these CNNMs, CNNM2 is expressed in the basolateral membrane of the kidney tubules where it is involved in Mg2+ reabsorption. A total of four patients, two of them with a suspected disorder of calcium metabolism, and two patients with a clinical diagnos ...[more]