Ontology highlight
ABSTRACT:
SUBMITTER: Basu S
PROVIDER: S-EPMC7527826 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Basu Soumya S Veeraraghavan Balaji B Ramaiah Sudha S Anbarasu Anand A
Microbial pathogenesis 20201001
No commercially available drug candidate has yet been devised which is unique to and not repurposed against SARS-CoV-2 and has high efficacy or safe toxicity profile or both. Taking curcumin as a reference compound, we identified a new commercially available cyclohexanone compound, ZINC07333416 with binding energy (-8.72 kcal/mol) better than that of popularly devised anti-Covid-19 drugs like viral protease inhibitor Lopinavir, nucleoside analogue Remdesivir and the repurposed drug hydroxychloro ...[more]