Ontology highlight
ABSTRACT:
SUBMITTER: Kim S
PROVIDER: S-EPMC7528686 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Kim Subin S Yeon Jungyoon J Sung Jongmin J Jin Mi Sun MS
Molecules and cells 20200901 9
The β-class of carbonic anhydrases (β-CAs) are zinc metalloenzymes widely distributed in the fungal kingdom that play essential roles in growth, survival, differentiation, and virulence by catalyzing the reversible interconversion of carbon dioxide (CO<sub>2</sub>) and bicarbonate (HCO<sub>3</sub><sup>-</sup>). Herein, we report the biochemical and crystallographic characterization of the β-CA CafA from the fungal pathogen <i>Aspergillus fumigatus</i>, the main causative agent of invasive asperg ...[more]