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Proteomic Analysis of Two Weight Classes of Mule Duck "foie gras" at the End of an Overfeeding Period.

ABSTRACT: The weight of the liver is one of the important selection criteria in the quality of "foie gras". This factor is highly variable despite the fact that individuals are reared, overfed and slaughtered in the same way. In this study, we performed an analysis of the proteome profile of two weight classes of light (between 550 and 599 g) and heavy (more than 700 g) livers. For the analysis of the proteic extracts, a liquid chromatographic analysis coupled with mass spectrometry was carried out. In low-weight livers, aerobic energy metabolism, protein metabolism and lipid metabolism oriented toward export and beta-oxidation were overexpressed. On the contrary, high weight livers were characterized by anaerobic energy metabolism and a more active protein catabolism associated with cell apoptosis and reorganization of the cell structure.

SUBMITTER: Lo B

PROVIDER: S-EPMC7528769 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Proteomic Analysis of Two Weight Classes of Mule Duck "foie gras" at the End of an Overfeeding Period.

Lo Bara B Marty-Gasset Nathalie N Pichereaux Carole C Bravo Céline C Manse Hélène H Domitile Renaud R Rémignon Hervé H

Frontiers in physiology 20200917

The weight of the liver is one of the important selection criteria in the quality of "foie gras". This factor is highly variable despite the fact that individuals are reared, overfed and slaughtered in the same way. In this study, we performed an analysis of the proteome profile of two weight classes of light (between 550 and 599 g) and heavy (more than 700 g) livers. For the analysis of the proteic extracts, a liquid chromatographic analysis coupled with mass spectrometry was carried out. In lo ...[more]

PMID: 33041868

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Project description:The weight liver is one of the important selection criteria in the quality of foie gras. This factor is highly variable despite the fact that individuals are reared, force-fed and slaughtered in the same way. In this study, an analysis of the proteome profile of two weight classes of light (between 550 g and 599 g) and heavy (more than 700 g) livers. For the analysis of the proteic extracts, a liquid chromatographic analysis coupled with mass spectrometry was carried out. In livers with low weight, aerobic energy metabolism, protein anabolism and lipid metabolism oriented towards export and beta-oxidation was overexpressed. However, high weight livers was characterized by anaerobic energy metabolism, more active protein catabolism associated with cell death by apoptosis and reorganisation of the cell structure.

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