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Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities of Nesfatin-1: A Review


ABSTRACT: Abstract Nesfatin-1, a newly identified energy-regulating peptide, is widely expressed in the central and peripheral tissues, and has a variety of physiological activities. A large number of recent studies have shown that nesfatin-1 exhibits antioxidant, anti-inflammatory, and anti-apoptotic properties and is involved in the occurrence and progression of various diseases. This review summarizes current data focusing on the therapeutic effects of nesfatin-1 under different pathophysiological conditions and the mechanisms underlying its antioxidant, anti-inflammatory, and anti-apoptotic activities.

SUBMITTER: Xu Y 

PROVIDER: S-EPMC7532075 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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