Diagnostic value of [18F]FDG PET/MRI for staging in patients with ovarian cancer.

ABSTRACT: PURPOSE:To evaluate the diagnostic potential of PET/MRI with 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) in ovarian cancer. MATERIALS AND METHODS:Participants comprised 103 patients with suspected ovarian cancer underwent pretreatment [18F]FDG PET/MRI, contrast-enhanced CT (ceCT) and pelvic dynamic contrast-enhanced MRI (ceMRI). Diagnostic performance of [18F]FDG PET/MRI and ceMRI for assessing the characterization and the extent of the primary tumor (T stage) and [18F]FDG PET/MRI and ceCT for assessing nodal (N stage) and distant (M stage) metastases was evaluated by two experienced readers. Histopathological and follow-up imaging results were used as the gold standard. The McNemar test was employed for statistical analysis. RESULTS:Accuracy for the characterization of suspected ovarian cancer was significantly better for [18F]FDG PET/MRI (92.5%) [95% confidence interval (CI) 0.84-0.95] than for ceMRI (80.6%) (95% CI 0.72-0.83) (p?

SUBMITTER: Tsuyoshi H 

PROVIDER: S-EPMC7532239 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature