Ontology highlight
ABSTRACT:
SUBMITTER: Koike Y
PROVIDER: S-EPMC7532542 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Koike Yuhki Y Li Bo B Ganji Niloofar N Zhu Haitao H Miyake Hiromu H Chen Yong Y Lee Carol C Janssen Lok Maarten M Zozaya Carlos C Lau Ethan E Lee Dorothy D Chusilp Sinobol S Zhang Zhen Z Yamoto Masaya M Wu Richard Y RY Inoue Mikihiro M Uchida Keiichi K Kusunoki Masato M Delgado-Olguin Paul P Mertens Luc L Daneman Alan A Eaton Simon S Sherman Philip M PM Pierro Agostino A
Nature communications 20201002 1
Necrotizing enterocolitis (NEC) is a devastating disease of premature infants with high mortality rate, indicating the need for precision treatment. NEC is characterized by intestinal inflammation and ischemia, as well derangements in intestinal microcirculation. Remote ischemic conditioning (RIC) has emerged as a promising tool in protecting distant organs against ischemia-induced damage. However, the effectiveness of RIC against NEC is unknown. To address this gap, we aimed to determine the ef ...[more]