Effect of obstructive sleep apnea on right ventricular ejection fraction in patients with hypertrophic obstructive cardiomyopathy.

ABSTRACT:

Background

Obstructive sleep apnea (OSA) is a common disease associated with worse structural and functional impairment of the heart in patients with hypertrophic obstructive cardiomyopathy (HOCM).

Hypothesis

The presence and severity of OSA can decrease the right ventricular ejection fraction (RVEF) in patients with HOCM.

Methods

In total, 151 consecutive patients with a confirmed diagnosis of HOCM at Fuwai Hospital between September 2017 and September 2018 were included. Polysomnography and cardiac magnetic resonance imaging were performed in all patients.

Results

Overall, 84 (55.6%) patients were diagnosed with OSA. The RVEF significantly decreased with the severity of OSA (none, mild, moderate-severe: 46.1 ± 8.2 vs 42.9 ± 7.5 vs 41.4 ± 7.4, P = .009). The a

SUBMITTER: Wang S 

PROVIDER: S-EPMC7534009 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature