Ontology highlight
ABSTRACT:
SUBMITTER: Wu C
PROVIDER: S-EPMC7534598 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
iScience 20201005 10
COVID-19 broke out in the end of December 2019 and is still spreading rapidly, which has been listed as an international concerning public health emergency. We found that the Spike protein of SARS-CoV-2 contains a furin cleavage site, which did not exist in any other betacoronavirus subtype B. Based on a series of analysis, we speculate that the presence of a redundant furin cut site in its Spike protein is responsible for SARS-CoV-2's stronger infectious nature than other coronaviruses, which l ...[more]